
OMVs also play a role in the pathogenesis as P. The stress responses encompass the production of outer membrane vesicles (OMVs) in a process of vesiculation that occurs during all phases of growth of Gram-negative bacteria. Mechanisms underlying the wide range of infections may entail the bacterial stress responses that help the microorganism to fit in new environments. For such a wide spectrum of infections, the molecular pathogenesis is still incompletely understood. IntroductionĪ Gram-negative bacterium, Pseudomonas aeruginosa has emerged as a prevalent nosocomial pathogen not only for hospital-acquired and medical device-related infections, but also for burn and war-wound infections. Thus, SOS plays a role in the vesiculation stimulation that contributes to cytotoxicity. OMV subproteomic analysis was performed to examine these factors, which reflected the OMV-mediated cytotoxicity and the physiology of the vesiculating cells under treatment and SOS. Obviously, the stimulated vesiculation is attributed by both SOS-related and unrelated factors. However, the further increase was suppressed in the lexAN strains, suggesting the SOS involvement. The levels of OMV proteins, lipids, and cytotoxicity increased for both the treated strains, demonstrating vesiculation stimulation by the antibiotic treatment. To test it, we conducted multiple analyses of outer membrane vesicles (OMVs) produced from the Pseudomonas aeruginosa wild type in which SOS is induced by ciprofloxacin and from the LexA noncleavable ( lexAN) strain in which SOS is repressed. This leads to a hypothesis concerning association of SOS with vesiculation. They are gunmetal.Bacterial infections can be aggravated by antibiotic treatment that induces SOS response and vesiculation. Daiwa added a 5.3:1 in the 400 which is a bottom fishing killer! The lefties are only available in 7.1:1. It is beautiful!ĭaiwa Lexa TW Baitcasting Reels are available for sale in 300 and 400 sizes in right and left handed models. That is amazing! If you fished a Lexa before, you are going to love the Daiwa Lexa TW Baitcasting Reel. You get all of these features and the reel weighs 12 ozs.

The reel has the magforce cast control system to help you out. I almost forgot to mention that Daiwa included their T-Wing system so if you fish topwater or want to do some surf fishing with this reel, you'll get more casting distance.


With over 28 lbs of drag, you are going to have a blast fighting bigger fish on smaller tackle! The ergonomic aluminum handle features an EVA ball knob that is really comfortable and won't get slippery when it gets wet or bloody. Engineer in eight corrosion resistant ball bearings and you've got a reel that is super smooth and can handle anything you throw at it. Daiwa pairs a brass main gear and a stainless steel pinion gear for power and durability. The difference between the two is the width of the spool. The Lexa TW comes in a 300 and 400 size but they share the same size body. The fist thing you'll notice about this baitcaster is the compact body design. Daiwa Lexa TW Baitcasting Reels take the Lexa brand name to new heights! Daiwa has gone all out with this reel adding a lot of features and completely restructuring the reel.
